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4u4u
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==Crystal structure of Lycorine bound to the yeast 80S ribosome== | ==Crystal structure of Lycorine bound to the yeast 80S ribosome== | ||
| - | <StructureSection load='4u4u' size='340' side='right' caption='[[4u4u]], [[Resolution|resolution]] 3.00Å' scene=''> | + | <StructureSection load='4u4u' size='340' side='right'caption='[[4u4u]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4u4u]] is a | + | <table><tr><td colspan='2'>[[4u4u]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ujk 4ujk], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ujl 4ujl], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ujm 4ujm], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ujn 4ujn] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ujo 4ujo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U4U FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3KD:(1S,2S,12BS,12CS)-2,4,5,7,12B,12C-HEXAHYDRO-1H-[1,3]DIOXOLO[4,5-J]PYRROLO[3,2,1-DE]PHENANTHRIDINE-1,2-DIOL'>3KD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3KD:(1S,2S,12BS,12CS)-2,4,5,7,12B,12C-HEXAHYDRO-1H-[1,3]DIOXOLO[4,5-J]PYRROLO[3,2,1-DE]PHENANTHRIDINE-1,2-DIOL'>3KD</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u4u OCA], [https://pdbe.org/4u4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u4u RCSB], [https://www.ebi.ac.uk/pdbsum/4u4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u4u ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSSA1_YEAST RSSA1_YEAST] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.<ref>PMID:9973221</ref> <ref>PMID:14627813</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4u4u" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Ribosome 3D structures|Ribosome 3D structures]] | *[[Ribosome 3D structures|Ribosome 3D structures]] | ||
| + | *[[3D sructureseceptor for activated protein kinase C 1|3D sructureseceptor for activated protein kinase C 1]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Saccharomyces cerevisiae | + | [[Category: Large Structures]] |
| - | [[Category: Loubresse | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: Prokhorova | + | [[Category: Garreau de Loubresse N]] |
| - | [[Category: Yusupov | + | [[Category: Prokhorova I]] |
| - | [[Category: Yusupova | + | [[Category: Yusupov M]] |
| - | + | [[Category: Yusupova G]] | |
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Current revision
Crystal structure of Lycorine bound to the yeast 80S ribosome
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