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4pc0

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==Structure of the human RbAp48-MTA1(670-711) complex==
==Structure of the human RbAp48-MTA1(670-711) complex==
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<StructureSection load='4pc0' size='340' side='right' caption='[[4pc0]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4pc0' size='340' side='right'caption='[[4pc0]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4pc0]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PC0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4pc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PC0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pby|4pby]], [[4pbz|4pbz]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pc0 RCSB], [http://www.ebi.ac.uk/pdbsum/4pc0 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pc0 OCA], [https://pdbe.org/4pc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pc0 RCSB], [https://www.ebi.ac.uk/pdbsum/4pc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pc0 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RBBP4_HUMAN RBBP4_HUMAN] Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.<ref>PMID:10866654</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4pc0" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Retinoblastoma-binding protein 3D structures|Retinoblastoma-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alqarni, S S.M]]
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[[Category: Homo sapiens]]
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[[Category: Laue, E D]]
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[[Category: Large Structures]]
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[[Category: Mackay, J P]]
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[[Category: Alqarni SSM]]
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[[Category: Silva, A P.G]]
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[[Category: Laue ED]]
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[[Category: Cell cycle]]
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[[Category: Mackay JP]]
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[[Category: Mta1-nurd subcomplex]]
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[[Category: Silva APG]]

Current revision

Structure of the human RbAp48-MTA1(670-711) complex

PDB ID 4pc0

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