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4uco
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Fragment bound to H.influenza NAD dependent DNA ligase== | |
| + | <StructureSection load='4uco' size='340' side='right'caption='[[4uco]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4uco]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UCO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D41:7-AMINO-2-TERT-BUTYL-4-(1H-PYRROL-2-YL)PYRIDO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE'>D41</scene>, <scene name='pdbligand=IWH:1-(2,4-DIMETHYLBENZYL)-6-OXO-1,6-DIHYDROPYRIDINE-3-CARBOXAMIDE'>IWH</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uco OCA], [https://pdbe.org/4uco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uco RCSB], [https://www.ebi.ac.uk/pdbsum/4uco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uco ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DNLJ_HAEIN DNLJ_HAEIN] DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[DNA ligase 3D structures|DNA ligase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Haemophilus influenzae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Boriack-Sjodin PA]] | ||
| + | [[Category: Brassington C]] | ||
| + | [[Category: Carcanague D]] | ||
| + | [[Category: Embrey K]] | ||
| + | [[Category: Eyermann CJ]] | ||
| + | [[Category: Giacobbe RA]] | ||
| + | [[Category: Gingipali L]] | ||
| + | [[Category: Gowravaram M]] | ||
| + | [[Category: Hale M]] | ||
| + | [[Category: Harang J]] | ||
| + | [[Category: Howard T]] | ||
| + | [[Category: Ioannidis G]] | ||
| + | [[Category: Jahic H]] | ||
| + | [[Category: Kutschke A]] | ||
| + | [[Category: Laganas VA]] | ||
| + | [[Category: Loch J]] | ||
| + | [[Category: Miller MD]] | ||
| + | [[Category: Murphy-Benenato KE]] | ||
| + | [[Category: Oguto H]] | ||
| + | [[Category: Otterbein L]] | ||
| + | [[Category: Patel SJ]] | ||
| + | [[Category: Shapiro AB]] | ||
Current revision
Fragment bound to H.influenza NAD dependent DNA ligase
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Categories: Haemophilus influenzae | Large Structures | Boriack-Sjodin PA | Brassington C | Carcanague D | Embrey K | Eyermann CJ | Giacobbe RA | Gingipali L | Gowravaram M | Hale M | Harang J | Howard T | Ioannidis G | Jahic H | Kutschke A | Laganas VA | Loch J | Miller MD | Murphy-Benenato KE | Oguto H | Otterbein L | Patel SJ | Shapiro AB
