3dnn

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==Molecular structure for the HIV-1 gp120 trimer in the unliganded state==
==Molecular structure for the HIV-1 gp120 trimer in the unliganded state==
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<StructureSection load='3dnn' size='340' side='right' caption='[[3dnn]], [[Resolution|resolution]] 20.00&Aring;' scene=''>
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<SX load='3dnn' size='340' side='right' viewer='molstar' caption='[[3dnn]], [[Resolution|resolution]] 20.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3dnn]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_hxb2r Hiv-1 m:b_hxb2r]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DNN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DNN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3dnn]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/HIV-1_M:B_HXB2R HIV-1 M:B_HXB2R]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DNN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DNN FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gc1|1gc1]], [[3dnl|3dnl]], [[3dno|3dno]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 20&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">env ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1 M:B_HXB2R])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dnn OCA], [https://pdbe.org/3dnn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dnn RCSB], [https://www.ebi.ac.uk/pdbsum/3dnn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dnn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dnn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dnn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dnn RCSB], [http://www.ebi.ac.uk/pdbsum/3dnn PDBsum]</span></td></tr>
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</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/3dnn_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dn/3dnn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dnn ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3dnn" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Gp120|Gp120]]
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*[[Gp120 3D structures|Gp120 3D structures]]
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*[[Hiv env proteins|Hiv env proteins]]
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== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Hiv-1 m:b_hxb2r]]
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[[Category: HIV-1 M:B_HXB2R]]
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[[Category: Bartesaghi, A]]
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[[Category: Large Structures]]
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[[Category: Borgnia, M J]]
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[[Category: Bartesaghi A]]
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[[Category: Liu, J]]
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[[Category: Borgnia MJ]]
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[[Category: Sapiro, G]]
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[[Category: Liu J]]
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[[Category: Subramaniam, S]]
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[[Category: Sapiro G]]
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[[Category: Aid]]
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[[Category: Subramaniam S]]
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[[Category: Apoptosis]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Envelope glycoprotein]]
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[[Category: Envelope protein]]
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[[Category: Fusion protein]]
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[[Category: Gp120]]
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[[Category: Hiv-1]]
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[[Category: Host-virus interaction]]
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[[Category: Immunodeficiency virus]]
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[[Category: Lipoprotein]]
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[[Category: Membrane]]
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[[Category: Palmitate]]
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[[Category: Viral immunoevasion]]
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[[Category: Viral protein]]
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[[Category: Virion]]
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Current revision

Molecular structure for the HIV-1 gp120 trimer in the unliganded state

3dnn, resolution 20.00Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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