This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3eq8
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors== | ==Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors== | ||
| - | <StructureSection load='3eq8' size='340' side='right' caption='[[3eq8]], [[Resolution|resolution]] 2.73Å' scene=''> | + | <StructureSection load='3eq8' size='340' side='right'caption='[[3eq8]], [[Resolution|resolution]] 2.73Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3eq8]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3eq8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EQ8 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.73Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=X98:1-{3-OXO-3-[(2S)-2-(PYRROLIDIN-1-YLCARBONYL)PYRROLIDIN-1-YL]PROPYL}-3-PHENYLQUINOXALIN-2(1H)-ONE'>X98</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3eq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3eq8 OCA], [https://pdbe.org/3eq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3eq8 RCSB], [https://www.ebi.ac.uk/pdbsum/3eq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3eq8 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PPCE_PIG PPCE_PIG] Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/3eq8_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eq/3eq8_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3eq8 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 26: | Line 28: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3eq8" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| Line 33: | Line 36: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Sus scrofa]] | [[Category: Sus scrofa]] | ||
| - | [[Category: Aranyi | + | [[Category: Aranyi P]] |
| - | [[Category: Bocskei | + | [[Category: Bocskei Z]] |
| - | [[Category: Ferenczy | + | [[Category: Ferenczy G]] |
| - | [[Category: Harmat | + | [[Category: Harmat V]] |
| - | [[Category: Hermecz | + | [[Category: Hermecz I]] |
| - | [[Category: Kanai | + | [[Category: Kanai K]] |
| - | [[Category: Naray-Szabo | + | [[Category: Naray-Szabo G]] |
| - | [[Category: Simon | + | [[Category: Simon K]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Prolyl oligopeptidase complexed with R-Pro-(decarboxy-Pro)-Type inhibitors
| |||||||||||
Categories: Large Structures | Sus scrofa | Aranyi P | Bocskei Z | Ferenczy G | Harmat V | Hermecz I | Kanai K | Naray-Szabo G | Simon K
