3i8c

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==Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A==
==Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A==
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<StructureSection load='3i8c' size='340' side='right' caption='[[3i8c]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='3i8c' size='340' side='right'caption='[[3i8c]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3i8c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3I8C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3i8c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I8C FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2b5m|2b5m]], [[3i7h|3i7h]], [[3i7k|3i7k]], [[3i7l|3i7l]], [[3i7n|3i7n]], [[3i7o|3i7o]], [[3i7p|3i7p]], [[3i89|3i89]], [[3i8e|3i8e]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DDB1, XAP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i8c OCA], [https://pdbe.org/3i8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i8c RCSB], [https://www.ebi.ac.uk/pdbsum/3i8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i8c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3i8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i8c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3i8c RCSB], [http://www.ebi.ac.uk/pdbsum/3i8c PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DCAF4_HUMAN DCAF4_HUMAN] May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.<ref>PMID:16949367</ref> <ref>PMID:16964240</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/3i8c_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i8/3i8c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i8c ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3i8c" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Breugel, P C.V]]
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[[Category: Large Structures]]
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[[Category: Li, T]]
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[[Category: Breugel PCV]]
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[[Category: Robert, E I]]
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[[Category: Li T]]
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[[Category: Strubin, M]]
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[[Category: Robert EI]]
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[[Category: Zheng, N]]
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[[Category: Strubin M]]
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[[Category: Dcaf4]]
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[[Category: Zheng N]]
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[[Category: Ddb1]]
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[[Category: Dna damage]]
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[[Category: Dna repair]]
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[[Category: Dna-binding]]
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[[Category: H-box motif]]
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[[Category: Host-virus interaction]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protein binding]]
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[[Category: Ubl conjugation pathway]]
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[[Category: Wd repeat]]
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[[Category: Wdr21a]]
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Current revision

Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR21A

PDB ID 3i8c

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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