This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1phq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:43, 16 August 2023) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1phq.jpg|left|200px]]
 
-
{{Structure
+
==Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP==
-
|PDB= 1phq |SIZE=350|CAPTION= <scene name='initialview01'>1phq</scene>, resolution 2.7&Aring;
+
<StructureSection load='1phq' size='340' side='right'caption='[[1phq]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=FPE:3-FLUORO-2-(PHOSPHONOOXY)PROPANOIC ACID'>FPE</scene>
+
<table><tr><td colspan='2'>[[1phq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PHQ FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-8-phosphooctulonate_synthase 3-deoxy-8-phosphooctulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.55 2.5.1.55]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
|GENE= KDSA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FPE:3-FLUORO-2-(PHOSPHONOOXY)PROPANOIC+ACID'>FPE</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1phq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1phq OCA], [https://pdbe.org/1phq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1phq RCSB], [https://www.ebi.ac.uk/pdbsum/1phq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1phq ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KDSA_ECOLI KDSA_ECOLI] Synthesis of KDO 8-P which is required for lipid A maturation and cellular growth.[HAMAP-Rule:MF_00056]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ph/1phq_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1phq ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP'''
+
==See Also==
-
 
+
*[[Kdo-8-phosphate synthase|Kdo-8-phosphate synthase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1PHQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PHQ OCA].
+
-
[[Category: 3-deoxy-8-phosphooctulonate synthase]]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Adir, N.]]
+
[[Category: Adir N]]
-
[[Category: Baasov, T.]]
+
[[Category: Baasov T]]
-
[[Category: Belakhov, V.]]
+
[[Category: Belakhov V]]
-
[[Category: Rabkin, E.]]
+
[[Category: Rabkin E]]
-
[[Category: Vainer, R.]]
+
[[Category: Vainer R]]
-
[[Category: FPE]]
+
-
[[Category: beta-alpha-barrel]]
+
-
[[Category: fluorinated analog]]
+
-
[[Category: lipopolysaccharide]]
+
-
[[Category: lyase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:24:30 2008''
+

Current revision

Crystal structure of KDO8P synthase in its binary complex with substrate analog E-FPEP

PDB ID 1phq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools