2m0y
From Proteopedia
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==Solution structure of the SH3 domain of DOCK180== | ==Solution structure of the SH3 domain of DOCK180== | ||
| - | <StructureSection load='2m0y' size='340' side='right' caption='[[2m0y | + | <StructureSection load='2m0y' size='340' side='right'caption='[[2m0y]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2m0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0Y FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0y OCA], [https://pdbe.org/2m0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0y RCSB], [https://www.ebi.ac.uk/pdbsum/2m0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0y ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DOCK1_MOUSE DOCK1_MOUSE] Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2m0y" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Dedicator of cytokinesis protein 3D structures|Dedicator of cytokinesis protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Liu | + | [[Category: Liu X]] |
| - | [[Category: Wen | + | [[Category: Wen W]] |
| - | + | ||
Current revision
Solution structure of the SH3 domain of DOCK180
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