1q1y

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[[Image:1q1y.gif|left|200px]]
 
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{{Structure
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==Crystal Structures of Peptide Deformylase from Staphylococcus aureus Complexed with Actinonin==
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|PDB= 1q1y |SIZE=350|CAPTION= <scene name='initialview01'>1q1y</scene>, resolution 1.9&Aring;
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<StructureSection load='1q1y' size='340' side='right'caption='[[1q1y]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>
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<table><tr><td colspan='2'>[[1q1y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q1Y FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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|GENE= SA1100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BB2:ACTINONIN'>BB2</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q1y OCA], [https://pdbe.org/1q1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q1y RCSB], [https://www.ebi.ac.uk/pdbsum/1q1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q1y ProSAT]</span></td></tr>
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</table>
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'''Crystal Structures of Peptide Deformylase from Staphylococcus aureus Complexed with Actinonin'''
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== Function ==
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[https://www.uniprot.org/uniprot/DEF_STAAU DEF_STAAU] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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1Q1Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q1Y OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q1/1q1y_consurf.spt"</scriptWhenChecked>
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Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent., Yoon HJ, Kim HL, Lee SK, Kim HW, Kim HW, Lee JY, Mikami B, Suh SW, Proteins. 2004 Nov 15;57(3):639-42. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15382235 15382235]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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[[Category: Peptide deformylase]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Single protein]]
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q1y ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Staphylococcus aureus]]
[[Category: Staphylococcus aureus]]
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[[Category: Kim, H L.]]
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[[Category: Kim HL]]
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[[Category: Kim, H W.]]
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[[Category: Kim HW]]
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[[Category: Lee, J Y.]]
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[[Category: Lee JY]]
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[[Category: Lee, S K.]]
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[[Category: Lee SK]]
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[[Category: Mikami, B.]]
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[[Category: Mikami B]]
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[[Category: Suh, S W.]]
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[[Category: Suh SW]]
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[[Category: Yoon, H J.]]
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[[Category: Yoon HJ]]
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[[Category: BB2]]
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[[Category: ZN]]
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[[Category: actinonin]]
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[[Category: metallo-enzyme]]
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[[Category: peptide deformylase]]
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[[Category: staphylococcus aureus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:32:01 2008''
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Current revision

Crystal Structures of Peptide Deformylase from Staphylococcus aureus Complexed with Actinonin

PDB ID 1q1y

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