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3n6u

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==Effector binding domain of TsaR in complex with its inducer p-toluenesulfonate==
==Effector binding domain of TsaR in complex with its inducer p-toluenesulfonate==
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<StructureSection load='3n6u' size='340' side='right' caption='[[3n6u]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
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<StructureSection load='3n6u' size='340' side='right'caption='[[3n6u]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3n6u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Comamonas_testosteroni Comamonas testosteroni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N6U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N6U FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3n6u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Comamonas_testosteroni Comamonas testosteroni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N6U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N6U FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3fxq|3fxq]], [[3fxr|3fxr]], [[3fxu|3fxu]], [[3fzj|3fzj]], [[3n6t|3n6t]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TSU:PARA-TOLUENE+SULFONATE'>TSU</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tsa, tsaR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=285 Comamonas testosteroni])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n6u OCA], [https://pdbe.org/3n6u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n6u RCSB], [https://www.ebi.ac.uk/pdbsum/3n6u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n6u ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n6u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n6u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n6u RCSB], [http://www.ebi.ac.uk/pdbsum/3n6u PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TSAR_COMTE TSAR_COMTE] Regulates expression of the tsaMBCD1 operon and of tsaT in response to p-toluenesulfonate (TSA). Acts by binding directly to the promoter region. Binding to the tsa promoter depends on TSA concentration.<ref>PMID:12676713</ref> <ref>PMID:13680097</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Comamonas testosteroni]]
[[Category: Comamonas testosteroni]]
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[[Category: Monferrer, D]]
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[[Category: Large Structures]]
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[[Category: Uson, I]]
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[[Category: Monferrer D]]
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[[Category: Rossmann fold]]
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[[Category: Uson I]]
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[[Category: Transcription regulator]]
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Current revision

Effector binding domain of TsaR in complex with its inducer p-toluenesulfonate

PDB ID 3n6u

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