3nby

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==Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex==
==Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex==
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<StructureSection load='3nby' size='340' side='right' caption='[[3nby]], [[Resolution|resolution]] 3.42&Aring;' scene=''>
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<StructureSection load='3nby' size='340' side='right'caption='[[3nby]], [[Resolution|resolution]] 3.42&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nby]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NBY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nby]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NBY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.42&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PKIA (GeneID: 5569) SNUPN (GeneID: 10073), RNUT1, SNUPN, SPN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), ARA24, OK/SW-cl.81, RAN, RAN (GeneID: 5901) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), Crm1, Xpo1, Xpo1 (GeneID: 103573) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nby OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nby RCSB], [http://www.ebi.ac.uk/pdbsum/3nby PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nby OCA], [https://pdbe.org/3nby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nby RCSB], [https://www.ebi.ac.uk/pdbsum/3nby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nby ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SPN1_HUMAN SPN1_HUMAN] Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.<ref>PMID:9670026</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3nby" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Exportin|Exportin]]
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*[[Exportin 3D structures|Exportin 3D structures]]
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*[[GTP-binding protein|GTP-binding protein]]
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*[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Corsini, L]]
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[[Category: Corsini L]]
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[[Category: Deichsel, D]]
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[[Category: Deichsel D]]
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[[Category: Ficner, R]]
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[[Category: Ficner R]]
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[[Category: Gorlich, D]]
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[[Category: Gorlich D]]
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[[Category: Guttler, T]]
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[[Category: Guttler T]]
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[[Category: Madl, T]]
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[[Category: Madl T]]
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[[Category: Monecke, T]]
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[[Category: Monecke T]]
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[[Category: Neumann, P]]
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[[Category: Neumann P]]
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[[Category: Sattler, M]]
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[[Category: Sattler M]]
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[[Category: Gtp-binding protein-transport protein complex]]
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[[Category: Protein transport]]
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Current revision

Crystal structure of the PKI NES-CRM1-RanGTP nuclear export complex

PDB ID 3nby

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