3oam

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==Crystal structure of cytidylyltransferase from Vibrio cholerae==
==Crystal structure of cytidylyltransferase from Vibrio cholerae==
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<StructureSection load='3oam' size='340' side='right' caption='[[3oam]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='3oam' size='340' side='right'caption='[[3oam]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3oam]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o1_biovar_el_tor Vibrio cholerae o1 biovar el tor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OAM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OAM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3oam]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OAM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">kdsB, VC1875, VC_1875 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=686 Vibrio cholerae O1 biovar El Tor])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-deoxy-manno-octulosonate_cytidylyltransferase 3-deoxy-manno-octulosonate cytidylyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.38 2.7.7.38] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3oam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oam OCA], [https://pdbe.org/3oam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3oam RCSB], [https://www.ebi.ac.uk/pdbsum/3oam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3oam ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3oam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3oam OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3oam RCSB], [http://www.ebi.ac.uk/pdbsum/3oam PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KDSB_VIBCH KDSB_VIBCH] Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/3oam_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oa/3oam_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3oam ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-deoxy-manno-octulosonate cytidylyltransferase]]
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[[Category: Large Structures]]
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[[Category: Vibrio cholerae o1 biovar el tor]]
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[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
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[[Category: Borek, D]]
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[[Category: Borek D]]
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[[Category: Structural genomic]]
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[[Category: Grimshaw S]]
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[[Category: Grimshaw, S]]
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[[Category: Hattne J]]
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[[Category: Hattne, J]]
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[[Category: Nakka C]]
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[[Category: Nakka, C]]
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[[Category: Otwinowski Z]]
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[[Category: Otwinowski, Z]]
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[[Category: Rostankowski R]]
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[[Category: Rostankowski, R]]
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[[Category: Csgid]]
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[[Category: Cytidylyltransferase]]
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[[Category: Transferase]]
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Current revision

Crystal structure of cytidylyltransferase from Vibrio cholerae

PDB ID 3oam

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