3qpt

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==Crystal structure of the Salmonella transcriptional regulator SlyA==
==Crystal structure of the Salmonella transcriptional regulator SlyA==
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<StructureSection load='3qpt' size='340' side='right' caption='[[3qpt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='3qpt' size='340' side='right'caption='[[3qpt]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qpt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica Salmonella enterica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QPT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qpt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QPT FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q5f|3q5f]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">slyA, STM1444 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28901 Salmonella enterica])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qpt OCA], [https://pdbe.org/3qpt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qpt RCSB], [https://www.ebi.ac.uk/pdbsum/3qpt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qpt ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qpt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qpt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qpt RCSB], [http://www.ebi.ac.uk/pdbsum/3qpt PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SLYA_SALTY SLYA_SALTY] Transcription regulator that can specifically activate or repress expression of target genes. Required for virulence and survival in the macrophage environment. Probably activates expression of ispA, xseB genes, and of omp operon.<ref>PMID:8544813</ref> <ref>PMID:9284144</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 3qpt" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Salmonella enterica]]
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[[Category: Large Structures]]
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[[Category: Dolan, K T]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Duguid, E M]]
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[[Category: Dolan KT]]
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[[Category: Marr/slya protein family]]
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[[Category: Duguid EM]]
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[[Category: Transcription]]
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[[Category: Transcriptonal regulator]]
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[[Category: Winged helix-turn-helix]]
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Current revision

Crystal structure of the Salmonella transcriptional regulator SlyA

PDB ID 3qpt

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