1r69

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[[Image:1r69.gif|left|200px]]
 
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{{Structure
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==STRUCTURE OF THE AMINO-TERMINAL DOMAIN OF PHAGE 434 REPRESSOR AT 2.0 ANGSTROMS RESOLUTION==
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|PDB= 1r69 |SIZE=350|CAPTION= <scene name='initialview01'>1r69</scene>, resolution 2.0&Aring;
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<StructureSection load='1r69' size='340' side='right'caption='[[1r69]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1r69]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Phage_434 Phage 434]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R69 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1R69 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1r69 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1r69 OCA], [https://pdbe.org/1r69 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1r69 RCSB], [https://www.ebi.ac.uk/pdbsum/1r69 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1r69 ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''STRUCTURE OF THE AMINO-TERMINAL DOMAIN OF PHAGE 434 REPRESSOR AT 2.0 ANGSTROMS RESOLUTION'''
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[https://www.uniprot.org/uniprot/RPC1_BP434 RPC1_BP434] Binds to two sets of three contiguous operator sites in the phage genome.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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The crystal structure of the amino-terminal domain of phage 434 repressor has been solved using molecular replacement methods and refined to an R-factor of 19.3% against data to 2.0 A resolution. The protein comprises five short alpha-helices. Two of these form a helix-turn-helix motif, very similar to those found in related proteins. The protein is remarkably similar to the Cro protein from the same phage.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r6/1r69_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1R69 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacteriophage_434 Bacteriophage 434]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R69 OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1r69 ConSurf].
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Structure of the amino-terminal domain of phage 434 repressor at 2.0 A resolution., Mondragon A, Subbiah S, Almo SC, Drottar M, Harrison SC, J Mol Biol. 1989 Jan 5;205(1):189-200. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2926803 2926803]
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<div style="clear:both"></div>
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[[Category: Bacteriophage 434]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Alamo, S C.]]
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[[Category: Large Structures]]
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[[Category: Drottar, M.]]
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[[Category: Phage 434]]
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[[Category: Harrison, S C.]]
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[[Category: Alamo SC]]
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[[Category: Mondragon, A.]]
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[[Category: Drottar M]]
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[[Category: Subbiah, S.]]
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[[Category: Harrison SC]]
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[[Category: gene regulating protein]]
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[[Category: Mondragon A]]
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[[Category: Subbiah S]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:47:23 2008''
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Current revision

STRUCTURE OF THE AMINO-TERMINAL DOMAIN OF PHAGE 434 REPRESSOR AT 2.0 ANGSTROMS RESOLUTION

PDB ID 1r69

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