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3s82

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==Structure of a S-adenosylmethionine synthetase from Mycobacterium avium==
==Structure of a S-adenosylmethionine synthetase from Mycobacterium avium==
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<StructureSection load='3s82' size='340' side='right' caption='[[3s82]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
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<StructureSection load='3s82' size='340' side='right'caption='[[3s82]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s82]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_avium Mycobacterium avium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3S82 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s82]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_avium_104 Mycobacterium avium 104]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S82 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">metK, MAV_3382 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1764 Mycobacterium avium])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_adenosyltransferase Methionine adenosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.6 2.5.1.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s82 OCA], [https://pdbe.org/3s82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s82 RCSB], [https://www.ebi.ac.uk/pdbsum/3s82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s82 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3s82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s82 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3s82 RCSB], [http://www.ebi.ac.uk/pdbsum/3s82 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METK_MYCA1 METK_MYCA1] Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme (By similarity).
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==See Also==
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*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Methionine adenosyltransferase]]
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[[Category: Large Structures]]
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[[Category: Mycobacterium avium]]
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[[Category: Mycobacterium avium 104]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
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[[Category: S-adenosylmethionine synthetase]]
 
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[[Category: Ssgcid]]
 
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[[Category: Transferase]]
 

Current revision

Structure of a S-adenosylmethionine synthetase from Mycobacterium avium

PDB ID 3s82

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