3taz
From Proteopedia
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==Crystal structure of NurA bound to dAMP and manganese== | ==Crystal structure of NurA bound to dAMP and manganese== | ||
| - | <StructureSection load='3taz' size='340' side='right' caption='[[3taz]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='3taz' size='340' side='right'caption='[[3taz]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3taz]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3taz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TAZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D5M:2-DEOXYADENOSINE-5-MONOPHOSPHATE'>D5M</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3taz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3taz OCA], [https://pdbe.org/3taz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3taz RCSB], [https://www.ebi.ac.uk/pdbsum/3taz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3taz ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NURA_PYRFU NURA_PYRFU] Involved in DNA double-strand break (DSB) repair (PubMed:18957200). Acts probably with HerA to stimulate resection of the 5' strand and produce the long 3' single-strand that is required for RadA loading (PubMed:18957200). Exhibits 5' endonuclease activity and both 5' and 3' exonuclease activities (PubMed:22064858).<ref>PMID:18957200</ref> <ref>PMID:22064858</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 3taz" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Pyrococcus furiosus | + | [[Category: Large Structures]] |
| - | [[Category: Chae | + | [[Category: Pyrococcus furiosus DSM 3638]] |
| - | [[Category: Cho | + | [[Category: Chae J]] |
| - | [[Category: Kim | + | [[Category: Cho Y]] |
| - | + | [[Category: Kim YC]] | |
| - | + | ||
Current revision
Crystal structure of NurA bound to dAMP and manganese
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