4fqb
From Proteopedia
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==crystal structure of toxic effector Tse1 in complex with immune protein Tsi1== | ==crystal structure of toxic effector Tse1 in complex with immune protein Tsi1== | ||
| - | <StructureSection load='4fqb' size='340' side='right' caption='[[4fqb]], [[Resolution|resolution]] 2.69Å' scene=''> | + | <StructureSection load='4fqb' size='340' side='right'caption='[[4fqb]], [[Resolution|resolution]] 2.69Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4fqb]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4fqb]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FQB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FQB FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.69Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fqb OCA], [https://pdbe.org/4fqb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fqb RCSB], [https://www.ebi.ac.uk/pdbsum/4fqb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fqb ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22700987, PubMed:22813741, PubMed:22931054). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22700987, PubMed:22931054).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Pseudomonas aeruginosa | + | [[Category: Large Structures]] |
| - | [[Category: Li | + | [[Category: Pseudomonas aeruginosa PAO1]] |
| - | [[Category: Wang | + | [[Category: Li L]] |
| - | [[Category: Zhang | + | [[Category: Wang T]] |
| - | + | [[Category: Zhang W]] | |
| - | + | ||
| - | + | ||
Current revision
crystal structure of toxic effector Tse1 in complex with immune protein Tsi1
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