We apologize for Proteopedia being slow to respond. For the past two years, a new implementation of Proteopedia has been being built. Soon, it will replace this 18-year old system. All existing content will be moved to the new system at a date that will be announced here.

4h0u

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (14:03, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP==
==Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP==
-
<StructureSection load='4h0u' size='340' side='right' caption='[[4h0u]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
+
<StructureSection load='4h0u' size='340' side='right'caption='[[4h0u]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4h0u]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Corynebacterium_glutamicum_atcc_13032 Corynebacterium glutamicum atcc 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4H0U FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4h0u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H0U FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cg0966, Cgl0844, thyA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196627 Corynebacterium glutamicum ATCC 13032])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0u OCA], [https://pdbe.org/4h0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h0u RCSB], [https://www.ebi.ac.uk/pdbsum/4h0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h0u ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4h0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4h0u RCSB], [http://www.ebi.ac.uk/pdbsum/4h0u PDBsum]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TYSY_CORGL TYSY_CORGL] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity).
==See Also==
==See Also==
-
*[[Thymidylate synthase|Thymidylate synthase]]
+
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Corynebacterium glutamicum atcc 13032]]
+
[[Category: Corynebacterium glutamicum ATCC 13032]]
-
[[Category: Thymidylate synthase]]
+
[[Category: Large Structures]]
-
[[Category: Chang, C M]]
+
[[Category: Chang CM]]
-
[[Category: Wang, W C]]
+
[[Category: Wang WC]]
-
[[Category: Dump]]
+
-
[[Category: Nucleotide]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP

PDB ID 4h0u

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools