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4g35
From Proteopedia
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==Mcl-1 in complex with a biphenyl cross-linked Noxa peptide.== | ==Mcl-1 in complex with a biphenyl cross-linked Noxa peptide.== | ||
| - | <StructureSection load='4g35' size='340' side='right' caption='[[4g35]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4g35' size='340' side='right'caption='[[4g35]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4g35]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4g35]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4G35 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4BP:4,4-BIS(BROMOMETHYL)BIPHENYL'>4BP</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4BP:4,4-BIS(BROMOMETHYL)BIPHENYL'>4BP</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=DCY:D-CYSTEINE'>DCY</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4g35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4g35 OCA], [https://pdbe.org/4g35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4g35 RCSB], [https://www.ebi.ac.uk/pdbsum/4g35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4g35 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MCL1_MOUSE MCL1_MOUSE] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4g35" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | [[Category: Drake | + | [[Category: Drake E]] |
| - | [[Category: Edwardraja | + | [[Category: Edwardraja S]] |
| - | [[Category: Gulick | + | [[Category: Gulick AM]] |
| - | [[Category: Lin | + | [[Category: Lin Q]] |
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Current revision
Mcl-1 in complex with a biphenyl cross-linked Noxa peptide.
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