4ig6

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==Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine==
==Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine==
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<StructureSection load='4ig6' size='340' side='right' caption='[[4ig6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='4ig6' size='340' side='right'caption='[[4ig6]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4ig6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_hz Anaplasma phagocytophilum hz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IG6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IG6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4ig6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anaplasma_phagocytophilum_str._HZ Anaplasma phagocytophilum str. HZ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IG6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3knu|3knu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APH_1267, trmD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=212042 Anaplasma phagocytophilum HZ])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ig6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ig6 OCA], [https://pdbe.org/4ig6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ig6 RCSB], [https://www.ebi.ac.uk/pdbsum/4ig6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ig6 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/tRNA_(guanine(37)-N(1))-methyltransferase tRNA (guanine(37)-N(1))-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.228 2.1.1.228] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ig6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ig6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ig6 RCSB], [http://www.ebi.ac.uk/pdbsum/4ig6 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRMD_ANAPZ TRMD_ANAPZ] Specifically methylates guanosine-37 in various tRNAs (By similarity).
==See Also==
==See Also==
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*[[TRNA methyltransferase|TRNA methyltransferase]]
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*[[TRNA methyltransferase 3D structures|TRNA methyltransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anaplasma phagocytophilum hz]]
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[[Category: Anaplasma phagocytophilum str. HZ]]
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[[Category: Structural genomic]]
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[[Category: Large Structures]]
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[[Category: G37]]
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[[Category: M1g]]
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[[Category: National institute of allergy and infectious disease]]
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[[Category: Natural inhibitor]]
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[[Category: Niaid]]
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[[Category: S-adenosyl homocysteine]]
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[[Category: S-adenosyl methionine-dependent]]
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[[Category: Sah]]
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[[Category: Sam]]
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[[Category: Ssgcid]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Trna]]
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[[Category: Trna modification]]
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Current revision

Crystal structure of a tRNA (guanine-N1)-methyltransferase from Anaplasma phagocytophilum bound to S-adenosylhomocysteine

PDB ID 4ig6

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