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4hzx

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==Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir==
==Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir==
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<StructureSection load='4hzx' size='340' side='right' caption='[[4hzx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4hzx' size='340' side='right'caption='[[4hzx]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4hzx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/swine/missouri/2124514/2006(h2n3)) Influenza a virus (a/swine/missouri/2124514/2006(h2n3))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HZX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HZX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4hzx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/swine/Missouri/2124514/2006(H2N3)) Influenza A virus (A/swine/Missouri/2124514/2006(H2N3))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HZX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HZX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ti6|3ti6]], [[4hzv|4hzv]], [[4hzw|4hzw]], [[4hzy|4hzy]], [[4hzz|4hzz]], [[4i00|4i00]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=489926 Influenza A virus (A/swine/Missouri/2124514/2006(H2N3))])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hzx OCA], [https://pdbe.org/4hzx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hzx RCSB], [https://www.ebi.ac.uk/pdbsum/4hzx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hzx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hzx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hzx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hzx RCSB], [http://www.ebi.ac.uk/pdbsum/4hzx PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A9YN63_9INFA A9YN63_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4hzx" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gao, G F]]
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[[Category: Large Structures]]
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[[Category: Li, Q]]
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[[Category: Gao GF]]
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[[Category: Qi, J]]
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[[Category: Li Q]]
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[[Category: Vavricka, C J]]
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[[Category: Qi J]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Vavricka CJ]]
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[[Category: Neuraminidase]]
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Current revision

Crystal structure of influenza A neuraminidase N3 complexed with oseltamivir

PDB ID 4hzx

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