4m67

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==Crystal structure of the human MLKL kinase-like domain==
==Crystal structure of the human MLKL kinase-like domain==
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<StructureSection load='4m67' size='340' side='right' caption='[[4m67]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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<StructureSection load='4m67' size='340' side='right'caption='[[4m67]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4m67]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M67 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M67 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4m67]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M67 FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4m66|4m66]], [[4m68|4m68]], [[4m69|4m69]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MLKL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m67 OCA], [https://pdbe.org/4m67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m67 RCSB], [https://www.ebi.ac.uk/pdbsum/4m67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m67 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m67 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m67 RCSB], [http://www.ebi.ac.uk/pdbsum/4m67 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MLKL_HUMAN MLKL_HUMAN] Required for the execution of programmed necrosis.<ref>PMID:22265414</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4m67" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Peng, W]]
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[[Category: Large Structures]]
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[[Category: Shi, Y]]
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[[Category: Peng W]]
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[[Category: Wu, J]]
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[[Category: Shi Y]]
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[[Category: Xie, T]]
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[[Category: Wu J]]
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[[Category: Yan, C]]
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[[Category: Xie T]]
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[[Category: A substrate of rip3]]
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[[Category: Yan C]]
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[[Category: Kinase-like]]
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[[Category: Rip3]]
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[[Category: Signaling protein]]
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Current revision

Crystal structure of the human MLKL kinase-like domain

PDB ID 4m67

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OCA

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