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4k1i

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==Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding==
==Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding==
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<StructureSection load='4k1i' size='340' side='right' caption='[[4k1i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='4k1i' size='340' side='right'caption='[[4k1i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4k1i]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus_(a/ri/5+/1957(h2n2)) Influenza a virus (a/ri/5+/1957(h2n2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K1I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4k1i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/RI/5+/1957(H2N2)) Influenza A virus (A/RI/5+/1957(H2N2))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K1I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K1I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=G39:(3R,4R,5S)-4-(ACETYLAMINO)-5-AMINO-3-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>G39</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4k1h|4k1h]], [[4k1j|4k1j]], [[4k1k|4k1k]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1i OCA], [https://pdbe.org/4k1i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k1i RCSB], [https://www.ebi.ac.uk/pdbsum/4k1i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k1i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k1i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k1i OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k1i RCSB], [http://www.ebi.ac.uk/pdbsum/4k1i PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q194T1_9INFA Q194T1_9INFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4k1i" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Neuraminidase|Neuraminidase]]
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*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Gao, F]]
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[[Category: Large Structures]]
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[[Category: Gao, G F]]
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[[Category: Gao F]]
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[[Category: Qi, J X]]
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[[Category: Gao GF]]
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[[Category: Wu, Y]]
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[[Category: Qi JX]]
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[[Category: Beta-propeller]]
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[[Category: Wu Y]]
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[[Category: Glycoside hydrolase enzyme]]
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[[Category: Hydrolase]]
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Current revision

Induced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor binding

PDB ID 4k1i

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