This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3wec

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:06, 8 November 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of P450 RauA (CYP1050A1) complexed with a biosynthetic intermediate of aurachin RE==
==Structure of P450 RauA (CYP1050A1) complexed with a biosynthetic intermediate of aurachin RE==
-
<StructureSection load='3wec' size='340' side='right' caption='[[3wec]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
+
<StructureSection load='3wec' size='340' side='right'caption='[[3wec]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3wec]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"mycobacterium_erythropolis"_gray_and_thornton_1928 "mycobacterium erythropolis" gray and thornton 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEC FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3wec]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEC FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AUI:3-[(2E,6E,9R)-9-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIEN-1-YL]-2-METHYLQUINOLIN-4(1H)-ONE'>AUI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rauA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1833 "Mycobacterium erythropolis" Gray and Thornton 1928])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AUI:3-[(2E,6E,9R)-9-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIEN-1-YL]-2-METHYLQUINOLIN-4(1H)-ONE'>AUI</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wec OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wec RCSB], [http://www.ebi.ac.uk/pdbsum/3wec PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wec FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wec OCA], [https://pdbe.org/3wec PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wec RCSB], [https://www.ebi.ac.uk/pdbsum/3wec PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wec ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/S6BVH1_RHOER S6BVH1_RHOER]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 15: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3wec" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
-
*[[Cytochrome P450|Cytochrome P450]]
+
*[[Cytochrome P450 3D structures|Cytochrome P450 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Mycobacterium erythropolis gray and thornton 1928]]
+
[[Category: Large Structures]]
-
[[Category: Kitagawa, W]]
+
[[Category: Rhodococcus erythropolis]]
-
[[Category: Tamura, T]]
+
[[Category: Kitagawa W]]
-
[[Category: Yasutake, Y]]
+
[[Category: Tamura T]]
-
[[Category: Cytosolic enzyme]]
+
[[Category: Yasutake Y]]
-
[[Category: Heme]]
+
-
[[Category: Oxidoreductase]]
+
-
[[Category: P450 fold]]
+

Current revision

Structure of P450 RauA (CYP1050A1) complexed with a biosynthetic intermediate of aurachin RE

PDB ID 3wec

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools