1szj

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:35, 14 February 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1szj.gif|left|200px]]
 
-
{{Structure
+
==STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION==
-
|PDB= 1szj |SIZE=350|CAPTION= <scene name='initialview01'>1szj</scene>, resolution 2.0&Aring;
+
<StructureSection load='1szj' size='340' side='right'caption='[[1szj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=ACT:Active+Site+Residues+CYS+149+And+HIS+176'>ACT</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
+
<table><tr><td colspan='2'>[[1szj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Panulirus_versicolor Panulirus versicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZJ FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.12 1.2.1.12]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1szj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1szj OCA], [https://pdbe.org/1szj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1szj RCSB], [https://www.ebi.ac.uk/pdbsum/1szj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1szj ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/G3P_PANVR G3P_PANVR]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1szj_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1szj ConSurf].
 +
<div style="clear:both"></div>
-
'''STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION'''
+
==See Also==
-
 
+
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]]
-
 
+
*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
-
==Overview==
+
__TOC__
-
When the active-site carboxymethylated D-glyceraldehyde-3-phosphate dehydrogenase is irradiated with ultraviolet light in the presence of NAD+, a fluorescent NAD derivative that is covalently linked to the enzyme is obtained. A preliminary crystallographic study of this fluorescent derivative, as well as of the native and the carboxymethylated enzymes from Palinurus versicolor, showed that they are isomorphous and belong to space group C2 as reported for the native enzyme from Palinurus vulgaris. The three forms of the enzyme, although they have identical unit cell parameters, differ considerably in their diffraction patterns, indicating marked differences in conformation in spite of the fact that they differ chemically only in a restricted region around the active site.
+
</StructureSection>
-
 
+
[[Category: Large Structures]]
-
==About this Structure==
+
[[Category: Panulirus versicolor]]
-
1SZJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Palinurus_versicolor Palinurus versicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZJ OCA].
+
[[Category: Li J]]
-
 
+
[[Category: Lin Z]]
-
==Reference==
+
[[Category: Song S]]
-
Preliminary crystallographic studies of lobster D-glyceraldehyde-3-phosphate dehydrogenase and the modified enzyme carrying the fluorescent derivative., Song SY, Gao YG, Zhou JM, Tsou CL, J Mol Biol. 1983 Dec 5;171(2):225-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/6655693 6655693]
+
-
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)]]
+
-
[[Category: Palinurus versicolor]]
+
-
[[Category: Single protein]]
+
-
[[Category: Li, J.]]
+
-
[[Category: Lin, Z.]]
+
-
[[Category: Song, S.]]
+
-
[[Category: NAD]]
+
-
[[Category: SO4]]
+
-
[[Category: allosterism]]
+
-
[[Category: d-glyceraldehyde-3-phosphate-dehydrogenase]]
+
-
[[Category: molecular symmetry]]
+
-
[[Category: oxidoreductase]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:11:38 2008''
+

Current revision

STRUCTURE OF HOLO-GLYCERALDEHYDE-3-PHOSPHATE-DEHYDROGENASE FROM PALINURUS VERSICOLOR REFINED 2.0 ANGSTROM RESOLUTION

PDB ID 1szj

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1szj"
Personal tools