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4gjw
From Proteopedia
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==Structure of the tetramerization domain of Nipah virus phosphoprotein== | ==Structure of the tetramerization domain of Nipah virus phosphoprotein== | ||
| - | <StructureSection load='4gjw' size='340' side='right' caption='[[4gjw]], [[Resolution|resolution]] 3.00Å' scene=''> | + | <StructureSection load='4gjw' size='340' side='right'caption='[[4gjw]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gjw]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gjw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Nipah_henipavirus Nipah henipavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GJW FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gjw OCA], [https://pdbe.org/4gjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gjw RCSB], [https://www.ebi.ac.uk/pdbsum/4gjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gjw ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PHOSP_NIPAV PHOSP_NIPAV] Essential component of the RNA polymerase transcription and replication complex. Binds the viral ribonucleocapsid and positions the L polymerase on the template (By similarity). May play a role to prevent the establishment of cellular antiviral state by binding to host STAT1 in the cytoplasm. This activity is not as strong as that of V and W. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Nipah henipavirus]] |
| - | [[Category: | + | [[Category: Jamin M]] |
| - | [[Category: | + | [[Category: Tarbouriech N]] |
| - | [[Category: | + | [[Category: Yabukarski F]] |
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Current revision
Structure of the tetramerization domain of Nipah virus phosphoprotein
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