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4nab

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==Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form==
==Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form==
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<StructureSection load='4nab' size='340' side='right' caption='[[4nab]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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<StructureSection load='4nab' size='340' side='right'caption='[[4nab]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4nab]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NAB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4nab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NAB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PCW:1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PCW</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3n8g|3n8g]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nab OCA], [https://pdbe.org/4nab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nab RCSB], [https://www.ebi.ac.uk/pdbsum/4nab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nab ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ATP2A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9986 European rabbit])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nab OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nab RCSB], [http://www.ebi.ac.uk/pdbsum/4nab PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4nab" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[ATPase 3D structures|ATPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Calcium-transporting ATPase]]
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[[Category: Large Structures]]
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[[Category: European rabbit]]
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[[Category: Oryctolagus cuniculus]]
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[[Category: Andersen, J P]]
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[[Category: Andersen JP]]
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[[Category: Arnou, B]]
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[[Category: Arnou B]]
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[[Category: Bublitz, M]]
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[[Category: Bublitz M]]
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[[Category: Clausen, J D]]
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[[Category: Clausen JD]]
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[[Category: Jaxel, C]]
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[[Category: Jaxel C]]
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[[Category: Maire, M le]]
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[[Category: Moller JV]]
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[[Category: Montigny, C]]
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[[Category: Montigny C]]
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[[Category: Mueller, J V]]
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[[Category: Nissen P]]
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[[Category: Nissen, P]]
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[[Category: Le Maire M]]
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[[Category: Calcium-transporting atpase]]
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[[Category: Hydrolase]]
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[[Category: Mutant e309q]]
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[[Category: P-type atpase]]
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[[Category: Sarcoplasmic reticulum]]
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Current revision

Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form

PDB ID 4nab

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