4iio
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide== | ==Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide== | ||
| - | <StructureSection load='4iio' size='340' side='right' caption='[[4iio]], [[Resolution|resolution]] 1.70Å' scene=''> | + | <StructureSection load='4iio' size='340' side='right'caption='[[4iio]], [[Resolution|resolution]] 1.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4iio]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4iio]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IIO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IIO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iio FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iio OCA], [https://pdbe.org/4iio PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iio RCSB], [https://www.ebi.ac.uk/pdbsum/4iio PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iio ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ITSN2_HUMAN ITSN2_HUMAN] Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR).<ref>PMID:19458185</ref> <ref>PMID:22648170</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Intersectin|Intersectin]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Arrowsmith | + | [[Category: Large Structures]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Dong | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Dong A]] |
| - | [[Category: Gu | + | [[Category: Edwards AM]] |
| - | [[Category: Guan | + | [[Category: Gu J]] |
| - | [[Category: Huang | + | [[Category: Guan X]] |
| - | + | [[Category: Huang H]] | |
| - | [[Category: Sidhu | + | [[Category: Sidhu S]] |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Tong | + | [[Category: Tong Y]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of the Second SH3 Domain of ITSN2 Bound with a Synthetic Peptide
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Dong A | Edwards AM | Gu J | Guan X | Huang H | Sidhu S | Tempel W | Tong Y
