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4izu

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==The E41Q mutant of the amidase from Nesterenkonia sp. AN1 showing the result of Michael addition of acrylamide at the active site cysteine==
==The E41Q mutant of the amidase from Nesterenkonia sp. AN1 showing the result of Michael addition of acrylamide at the active site cysteine==
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<StructureSection load='4izu' size='340' side='right' caption='[[4izu]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
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<StructureSection load='4izu' size='340' side='right'caption='[[4izu]], [[Resolution|resolution]] 1.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4izu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nesterenkonia_sp._10004 Nesterenkonia sp. 10004]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IZU FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4izu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nesterenkonia_sp._10004 Nesterenkonia sp. 10004]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IZU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IZU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1HC:PROP-2-ENAMIDE'>1HC</scene>, <scene name='pdbligand=ROP:PROPIONAMIDE'>ROP</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HC:PROP-2-ENAMIDE'>1HC</scene>, <scene name='pdbligand=ROP:PROPIONAMIDE'>ROP</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hkx|3hkx]], [[4izs|4izs]], [[4izt|4izt]], [[4izv|4izv]], [[4izw|4izw]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4izu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4izu OCA], [https://pdbe.org/4izu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4izu RCSB], [https://www.ebi.ac.uk/pdbsum/4izu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4izu ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Nit2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=501897 Nesterenkonia sp. 10004])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Amidase Amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.4 3.5.1.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4izu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4izu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4izu RCSB], [http://www.ebi.ac.uk/pdbsum/4izu PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0VWZ1_9MICC D0VWZ1_9MICC]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Amidase]]
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[[Category: Large Structures]]
[[Category: Nesterenkonia sp. 10004]]
[[Category: Nesterenkonia sp. 10004]]
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[[Category: Kimani, S W]]
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[[Category: Kimani SW]]
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[[Category: Sewell, B T]]
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[[Category: Sewell BT]]
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[[Category: Cysteine 145]]
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[[Category: Hydrolase]]
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[[Category: Propionamide]]
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Current revision

The E41Q mutant of the amidase from Nesterenkonia sp. AN1 showing the result of Michael addition of acrylamide at the active site cysteine

PDB ID 4izu

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