This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1t3y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:30, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1t3y.gif|left|200px]]
 
-
{{Structure
+
==Three Crystal Structures of Human Coactosin-like Protein==
-
|PDB= 1t3y |SIZE=350|CAPTION= <scene name='initialview01'>1t3y</scene>, resolution 1.15&Aring;
+
<StructureSection load='1t3y' size='340' side='right'caption='[[1t3y]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1t3y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T3Y FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
-
|GENE=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t3y OCA], [https://pdbe.org/1t3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t3y RCSB], [https://www.ebi.ac.uk/pdbsum/1t3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t3y ProSAT]</span></td></tr>
-
}}
+
</table>
-
 
+
== Function ==
-
'''Three Crystal Structures of Human Coactosin-like Protein'''
+
[https://www.uniprot.org/uniprot/COTL1_HUMAN COTL1_HUMAN] Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization.<ref>PMID:11583571</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==Disease==
+
Check<jmol>
-
Known disease associated with this structure: Cardiomyopathy, dilated, 1M OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=600824 600824]]
+
<jmolCheckbox>
-
 
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t3/1t3y_consurf.spt"</scriptWhenChecked>
-
==About this Structure==
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
1T3Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3Y OCA].
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t3y ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Chen, Z.]]
+
[[Category: Chen Z]]
-
[[Category: Liu, L.]]
+
[[Category: Liu L]]
-
[[Category: Wang, Y.]]
+
[[Category: Wang Y]]
-
[[Category: Wei, Z.]]
+
[[Category: Wei Z]]
-
[[Category: beta sheet]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:13:26 2008''
+

Current revision

Three Crystal Structures of Human Coactosin-like Protein

PDB ID 1t3y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools