1x5v
From Proteopedia
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==NMR Structure of PcFK1== | ==NMR Structure of PcFK1== | ||
| - | <StructureSection load='1x5v' size='340' side='right' caption='[[1x5v | + | <StructureSection load='1x5v' size='340' side='right'caption='[[1x5v]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1x5v]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1x5v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Psalmopoeus_cambridgei Psalmopoeus cambridgei]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1X5V FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HSL:HOMOSERINE+LACTONE'>HSL</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1x5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1x5v OCA], [https://pdbe.org/1x5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1x5v RCSB], [https://www.ebi.ac.uk/pdbsum/1x5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1x5v ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NTA_PSACA NTA_PSACA] Possesses strong antiplasmodial activity against the intra-erythrocyte stage of P.falciparum in vitro. IC(50) for inhibiting P.falciparum growth is 1.59 uM. Interacts with infected and healthy erythrocytes. Does not lyse erythrocytes, is not cytotoxic to nucleated mammalian cells, and does not inhibit neuromuscular function. Has neither antibacterial nor antifungal activity.<ref>PMID:15304333</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1x5v" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Psalmopoeus cambridgei]] | [[Category: Psalmopoeus cambridgei]] | ||
| - | [[Category: Camadro | + | [[Category: Camadro JM]] |
| - | [[Category: Chagot | + | [[Category: Chagot B]] |
| - | [[Category: Choi | + | [[Category: Choi SJ]] |
| - | [[Category: Darbon | + | [[Category: Darbon H]] |
| - | [[Category: Guette | + | [[Category: Guette C]] |
| - | [[Category: Pimentel | + | [[Category: Pimentel C]] |
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Current revision
NMR Structure of PcFK1
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