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1th4

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[[Image:1th4.gif|left|200px]]
 
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{{Structure
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==crystal structure of NADPH depleted bovine liver catalase complexed with 3-amino-1,2,4-triazole==
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|PDB= 1th4 |SIZE=350|CAPTION= <scene name='initialview01'>1th4</scene>, resolution 2.98&Aring;
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<StructureSection load='1th4' size='340' side='right'caption='[[1th4]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=3TR:3-AMINO-1,2,4-TRIAZOLE'>3TR</scene> and <scene name='pdbligand=HEM:PROTOPORPHYRIN IX CONTAINING FE'>HEM</scene>
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<table><tr><td colspan='2'>[[1th4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TH4 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Catalase Catalase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.6 1.11.1.6]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.98&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3TR:3-AMINO-1,2,4-TRIAZOLE'>3TR</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1th4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1th4 OCA], [https://pdbe.org/1th4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1th4 RCSB], [https://www.ebi.ac.uk/pdbsum/1th4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1th4 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CATA_BOVIN CATA_BOVIN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/th/1th4_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1th4 ConSurf].
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<div style="clear:both"></div>
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'''crystal structure of NADPH depleted bovine liver catalase complexed with 3-amino-1,2,4-triazole'''
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==See Also==
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*[[Catalase 3D structures|Catalase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1TH4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TH4 OCA].
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Catalase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Kumaran D]]
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[[Category: Kumaran, D.]]
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[[Category: Ponnuswamy MN]]
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[[Category: Ponnuswamy, M N.]]
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[[Category: Sekar K]]
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[[Category: Sekar, K.]]
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[[Category: Sugadev R]]
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[[Category: Sugadev, R.]]
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[[Category: Swaminathan S]]
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[[Category: Swaminathan, S.]]
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[[Category: 3TR]]
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[[Category: HEM]]
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[[Category: 2]]
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[[Category: 3-amino-1]]
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[[Category: 4-triazole]]
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[[Category: bovine liver catalase]]
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[[Category: nadph]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:18:14 2008''
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Current revision

crystal structure of NADPH depleted bovine liver catalase complexed with 3-amino-1,2,4-triazole

PDB ID 1th4

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