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1tj6

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[[Image:1tj6.gif|left|200px]]
 
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{{Structure
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==Crystal structure of the Xenopus tropicalis Spred1 EVH-1 domain==
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|PDB= 1tj6 |SIZE=350|CAPTION= <scene name='initialview01'>1tj6</scene>, resolution 1.65&Aring;
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<StructureSection load='1tj6' size='340' side='right'caption='[[1tj6]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1tj6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_tropicalis Xenopus tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TJ6 FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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|GENE= Spred1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8364 Xenopus tropicalis])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tj6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tj6 OCA], [https://pdbe.org/1tj6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tj6 RCSB], [https://www.ebi.ac.uk/pdbsum/1tj6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tj6 ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal structure of the Xenopus tropicalis Spred1 EVH-1 domain'''
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[https://www.uniprot.org/uniprot/SPRE1_XENTR SPRE1_XENTR] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1TJ6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Xenopus_tropicalis Xenopus tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TJ6 OCA].
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<jmolCheckbox>
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[[Category: Protein complex]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tj/1tj6_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tj6 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Xenopus tropicalis]]
[[Category: Xenopus tropicalis]]
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[[Category: Amaya, E.]]
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[[Category: Amaya E]]
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[[Category: Blundell, T L.]]
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[[Category: Blundell TL]]
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[[Category: Harmer, N J.]]
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[[Category: Harmer NJ]]
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[[Category: Sivak, J.]]
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[[Category: Sivak J]]
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[[Category: evh-1]]
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[[Category: spred]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:19:04 2008''
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Current revision

Crystal structure of the Xenopus tropicalis Spred1 EVH-1 domain

PDB ID 1tj6

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