1tqj

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[[Image:1tqj.gif|left|200px]]
 
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{{Structure
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==Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution==
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|PDB= 1tqj |SIZE=350|CAPTION= <scene name='initialview01'>1tqj</scene>, resolution 1.60&Aring;
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<StructureSection load='1tqj' size='340' side='right'caption='[[1tqj]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1tqj]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TQJ FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Ribulose-phosphate_3-epimerase Ribulose-phosphate 3-epimerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.3.1 5.1.3.1]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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|GENE= RPE, SLL0807 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1143 Synechocystis sp.])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tqj OCA], [https://pdbe.org/1tqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tqj RCSB], [https://www.ebi.ac.uk/pdbsum/1tqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tqj ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution'''
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[https://www.uniprot.org/uniprot/RPE_SYNY3 RPE_SYNY3] Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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The crystal structure of D-ribulose 5-phosphate 3-epimerase (RPE) from the cyanobacterium Synechocystis was determined by X-ray crystallography to 1.6 A resolution. The enzyme, which catalyzes the epimerization of D-ribulose 5-phosphate and D-xylulose 5-phosphate, assembles as a hexamer of (beta/alpha)(8)-barrels in the crystallographic asymmetric unit. The active site is highly similar to those of two previously reported RPEs and provides further evidence for essential catalytic roles for several active-site residues.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tq/1tqj_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1TQJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Synechocystis_sp. Synechocystis sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TQJ OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tqj ConSurf].
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Structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 A resolution., Wise EL, Akana J, Gerlt JA, Rayment I, Acta Crystallogr D Biol Crystallogr. 2004 Sep;60(Pt 9):1687-90. Epub 2004, Aug 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15333955 15333955]
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<div style="clear:both"></div>
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[[Category: Ribulose-phosphate 3-epimerase]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Synechocystis sp.]]
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[[Category: Large Structures]]
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[[Category: Akana, J.]]
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[[Category: Synechocystis sp]]
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[[Category: Gerlt, J A.]]
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[[Category: Akana J]]
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[[Category: Rayment, I.]]
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[[Category: Gerlt JA]]
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[[Category: Wise, E L.]]
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[[Category: Rayment I]]
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[[Category: beta-alpha barrel epimerase]]
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[[Category: Wise EL]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:21:51 2008''
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Current revision

Crystal structure of D-ribulose 5-phosphate 3-epimerase from Synechocystis to 1.6 angstrom resolution

PDB ID 1tqj

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