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1uyq

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[[Image:1uyq.gif|left|200px]]
 
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{{Structure
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==mutated b-glucosidase A from Paenibacillus polymyxa showing increased stability==
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|PDB= 1uyq |SIZE=350|CAPTION= <scene name='initialview01'>1uyq</scene>, resolution 2.2&Aring;
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<StructureSection load='1uyq' size='340' side='right'caption='[[1uyq]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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|SITE= <scene name='pdbsite=CAT:Nfg+Binding+Site+For+Chain+A'>CAT</scene>
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=G2F:2-DEOXY-2FLUORO-GLUCOSE'>G2F</scene> and <scene name='pdbligand=NFG:2,4-DINITROPHENYL 2-DEOXY-2-FLUORO-BETA-D-GLUCOPYRANOSIDE'>NFG</scene>
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<table><tr><td colspan='2'>[[1uyq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paenibacillus_polymyxa Paenibacillus polymyxa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UYQ FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G2F:2-DEOXY-2-FLUORO-ALPHA-D-GLUCOPYRANOSE'>G2F</scene>, <scene name='pdbligand=NFG:2,4-DINITROPHENYL+2-DEOXY-2-FLUORO-BETA-D-GLUCOPYRANOSIDE'>NFG</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uyq OCA], [https://pdbe.org/1uyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uyq RCSB], [https://www.ebi.ac.uk/pdbsum/1uyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uyq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BGLA_PAEPO BGLA_PAEPO] BglA is intracellular and cleaves cellobiose probably through inorganic phosphate mediated hydrolysis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/1uyq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uyq ConSurf].
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<div style="clear:both"></div>
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'''MUTATED B-GLUCOSIDASE A FROM PAENIBACILLUS POLYMYXA SHOWING INCREASED STABILITY'''
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==See Also==
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*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1UYQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Paenibacillus_polymyxa Paenibacillus polymyxa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UYQ OCA].
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[[Category: Large Structures]]
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[[Category: Beta-glucosidase]]
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[[Category: Paenibacillus polymyxa]]
[[Category: Paenibacillus polymyxa]]
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[[Category: Single protein]]
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[[Category: Isorna P]]
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[[Category: Isorna, P.]]
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[[Category: Polaina J]]
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[[Category: Polaina, J.]]
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[[Category: Sanz-Aparicio J]]
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[[Category: Sanz-Aparicio, J.]]
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[[Category: G2F]]
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[[Category: NFG]]
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[[Category: b-glucosidase]]
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[[Category: cellulose degradation]]
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[[Category: hydrolase glycosidase]]
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[[Category: mutation affecting stability]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:38:40 2008''
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Current revision

mutated b-glucosidase A from Paenibacillus polymyxa showing increased stability

PDB ID 1uyq

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