1uz1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:04, 13 December 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1uz1.jpg|left|200px]]
 
-
{{Structure
+
==Family 1 b-glucosidase from Thermotoga maritima in complex with isofagomine lactam==
-
|PDB= 1uz1 |SIZE=350|CAPTION= <scene name='initialview01'>1uz1</scene>, resolution 2.00&Aring;
+
<StructureSection load='1uz1' size='340' side='right'caption='[[1uz1]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
|SITE= <scene name='pdbsite=AC1:Ifl+Binding+Site+For+Chain+B'>AC1</scene>
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=IFL:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE'>IFL</scene>
+
<table><tr><td colspan='2'>[[1uz1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZ1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UZ1 FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IFL:(3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE'>IFL</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uz1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uz1 OCA], [https://pdbe.org/1uz1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uz1 RCSB], [https://www.ebi.ac.uk/pdbsum/1uz1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uz1 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/BGLA_THEMA BGLA_THEMA]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uz/1uz1_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uz1 ConSurf].
 +
<div style="clear:both"></div>
-
'''FAMILY 1 B-GLUCOSIDASE FROM THERMOTOGA MARITIMA IN COMPLEX WITH ISOFAGOMINE LACTAM'''
+
==See Also==
-
 
+
*[[Beta-glucosidase 3D structures|Beta-glucosidase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1UZ1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZ1 OCA].
+
[[Category: Large Structures]]
-
 
+
-
==Reference==
+
-
Common inhibition of both beta-glucosidases and beta-mannosidases by isofagomine lactam reflects different conformational itineraries for pyranoside hydrolysis., Vincent F, Gloster TM, Macdonald J, Morland C, Stick RV, Dias FM, Prates JA, Fontes CM, Gilbert HJ, Davies GJ, Chembiochem. 2004 Nov 5;5(11):1596-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15515081 15515081]
+
-
[[Category: Beta-glucosidase]]
+
-
[[Category: Single protein]]
+
[[Category: Thermotoga maritima]]
[[Category: Thermotoga maritima]]
-
[[Category: Davies, G J.]]
+
[[Category: Davies GJ]]
-
[[Category: Gloster, T M.]]
+
[[Category: Gloster TM]]
-
[[Category: Macdonald, J.]]
+
[[Category: Macdonald J]]
-
[[Category: Stick, R V.]]
+
[[Category: Stick RV]]
-
[[Category: IFL]]
+
-
[[Category: enzyme]]
+
-
[[Category: family gh1]]
+
-
[[Category: glucoside hydrolysis]]
+
-
[[Category: hydrolase]]
+
-
[[Category: isofagomine lactam]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:38:48 2008''
+

Current revision

Family 1 b-glucosidase from Thermotoga maritima in complex with isofagomine lactam

PDB ID 1uz1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1uz1"
Personal tools