1v9j

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[[Image:1v9j.jpg|left|200px]]
 
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{{Structure
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==Solution structure of a BolA-like protein from Mus musculus==
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|PDB= 1v9j |SIZE=350|CAPTION= <scene name='initialview01'>1v9j</scene>
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<StructureSection load='1v9j' size='340' side='right'caption='[[1v9j]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1v9j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1iw5 1iw5]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V9J FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE=
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v9j OCA], [https://pdbe.org/1v9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v9j RCSB], [https://www.ebi.ac.uk/pdbsum/1v9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v9j ProSAT], [https://www.topsan.org/Proteins/RSGI/1v9j TOPSAN]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Solution structure of a BolA-like protein from Mus musculus'''
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[https://www.uniprot.org/uniprot/BOLA2_MOUSE BOLA2_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==Overview==
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v9j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v9j ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
The BolA-like proteins are widely conserved from prokaryotes to eukaryotes. The BolA-like proteins seem to be involved in cell proliferation or cell-cycle regulation, but the molecular function is still unknown. Here we determined the structure of a mouse BolA-like protein. The overall topology is alphabetabetaalphaalphabetaalpha, in which beta(1) and beta(2) are antiparallel, and beta(3) is parallel to beta(2). This fold is similar to the class II KH fold, except for the absence of the GXXG loop, which is well conserved in the KH fold. The conserved residues in the BolA-like proteins are assembled on the one side of the protein.
The BolA-like proteins are widely conserved from prokaryotes to eukaryotes. The BolA-like proteins seem to be involved in cell proliferation or cell-cycle regulation, but the molecular function is still unknown. Here we determined the structure of a mouse BolA-like protein. The overall topology is alphabetabetaalphaalphabetaalpha, in which beta(1) and beta(2) are antiparallel, and beta(3) is parallel to beta(2). This fold is similar to the class II KH fold, except for the absence of the GXXG loop, which is well conserved in the KH fold. The conserved residues in the BolA-like proteins are assembled on the one side of the protein.
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==About this Structure==
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Solution structure of a BolA-like protein from Mus musculus.,Kasai T, Inoue M, Koshiba S, Yabuki T, Aoki M, Nunokawa E, Seki E, Matsuda T, Matsuda N, Tomo Y, Shirouzu M, Terada T, Obayashi N, Hamana H, Shinya N, Tatsuguchi A, Yasuda S, Yoshida M, Hirota H, Matsuo Y, Tani K, Suzuki H, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Kigawa T, Yokoyama S Protein Sci. 2004 Feb;13(2):545-8. Epub 2004 Jan 10. PMID:14718656<ref>PMID:14718656</ref>
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1V9J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry 1IW5. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V9J OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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Solution structure of a BolA-like protein from Mus musculus., Kasai T, Inoue M, Koshiba S, Yabuki T, Aoki M, Nunokawa E, Seki E, Matsuda T, Matsuda N, Tomo Y, Shirouzu M, Terada T, Obayashi N, Hamana H, Shinya N, Tatsuguchi A, Yasuda S, Yoshida M, Hirota H, Matsuo Y, Tani K, Suzuki H, Arakawa T, Carninci P, Kawai J, Hayashizaki Y, Kigawa T, Yokoyama S, Protein Sci. 2004 Feb;13(2):545-8. Epub 2004 Jan 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14718656 14718656]
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</div>
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<div class="pdbe-citations 1v9j" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Aoki M]]
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[[Category: Aoki, M.]]
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[[Category: Arakawa T]]
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[[Category: Arakawa, T.]]
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[[Category: Carninci P]]
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[[Category: Carninci, P.]]
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[[Category: Hamana H]]
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[[Category: Hamana, H.]]
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[[Category: Hayashizaki Y]]
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[[Category: Hayashizaki, Y.]]
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[[Category: Hirota H]]
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[[Category: Hirota, H.]]
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[[Category: Inoue M]]
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[[Category: Inoue, M.]]
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[[Category: Kasai T]]
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[[Category: Kasai, T.]]
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[[Category: Kawai J]]
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[[Category: Kawai, J.]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T.]]
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[[Category: Koshiba S]]
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[[Category: Koshiba, S.]]
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[[Category: Matsuda N]]
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[[Category: Matsuda, N.]]
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[[Category: Matsuda T]]
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[[Category: Matsuda, T.]]
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[[Category: Matsuo Y]]
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[[Category: Matsuo, Y.]]
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[[Category: Nunokawa E]]
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[[Category: Nunokawa, E.]]
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[[Category: Obayashi N]]
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[[Category: Obayashi, N.]]
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[[Category: Seki E]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Shinya N]]
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[[Category: Seki, E.]]
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[[Category: Shirouzu M]]
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[[Category: Shinya, N.]]
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[[Category: Suzuki H]]
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[[Category: Shirouzu, M.]]
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[[Category: Tani K]]
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[[Category: Suzuki, H.]]
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[[Category: Tatsuguchi A]]
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[[Category: Tani, K.]]
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[[Category: Terada T]]
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[[Category: Tatsuguchi, A.]]
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[[Category: Tomo Y]]
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[[Category: Terada, T.]]
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[[Category: Yabuki T]]
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[[Category: Tomo, Y.]]
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[[Category: Yasuda S]]
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[[Category: Yabuki, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yasuda, S.]]
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[[Category: Yoshida M]]
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[[Category: Yokoyama, S.]]
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[[Category: Yoshida, M.]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: stationary phase morphogene]]
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[[Category: stress-induced morphogene]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:42:36 2008''
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Current revision

Solution structure of a BolA-like protein from Mus musculus

PDB ID 1v9j

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