This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vbi

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:01, 28 December 2023) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1vbi.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus HB8==
-
|PDB= 1vbi |SIZE=350|CAPTION= <scene name='initialview01'>1vbi</scene>, resolution 1.80&Aring;
+
<StructureSection load='1vbi' size='340' side='right'caption='[[1vbi]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>
+
<table><tr><td colspan='2'>[[1vbi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBI FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase L-lactate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.27 1.1.1.27]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbi OCA], [https://pdbe.org/1vbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbi RCSB], [https://www.ebi.ac.uk/pdbsum/1vbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbi ProSAT], [https://www.topsan.org/Proteins/RSGI/1vbi TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q53W84_THET8 Q53W84_THET8]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vb/1vbi_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vbi ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus HB8'''
+
==See Also==
-
 
+
*[[Lactate dehydrogenase 3D structures|Lactate dehydrogenase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1VBI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBI OCA].
+
[[Category: Large Structures]]
-
[[Category: L-lactate dehydrogenase]]
+
-
[[Category: Single protein]]
+
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
-
[[Category: Kunishima, N.]]
+
[[Category: Kunishima N]]
-
[[Category: Mizutani, H.]]
+
[[Category: Mizutani H]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
-
[[Category: EDO]]
+
-
[[Category: NAD]]
+
-
[[Category: SO4]]
+
-
[[Category: malate dehydrogenase]]
+
-
[[Category: nad(p) binding protein]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: structural genomic]]
+
-
[[Category: thermus thermophilus hb8]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:43:21 2008''
+

Current revision

Crystal structure of type 2 malate/lactate dehydrogenase from thermus thermophilus HB8

PDB ID 1vbi

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools