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1g92

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==SOLUTION STRUCTURE OF PONERATOXIN==
==SOLUTION STRUCTURE OF PONERATOXIN==
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<StructureSection load='1g92' size='340' side='right' caption='[[1g92]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
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<StructureSection load='1g92' size='340' side='right'caption='[[1g92]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1g92]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G92 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G92 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1g92]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paraponera_clavata Paraponera clavata]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G92 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g92 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g92 RCSB], [http://www.ebi.ac.uk/pdbsum/1g92 PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g92 OCA], [https://pdbe.org/1g92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g92 RCSB], [https://www.ebi.ac.uk/pdbsum/1g92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g92 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TX1A_PARCV TX1A_PARCV] Blocks nicotinic synaptic transmission in insect CNS and affects voltage-gated sodium channels (Nav). It is a strong, but very slowly acting agonist for smooth muscles and its blocks synaptic transmission in the insect CNS in a concentration-dependent manner and depolarizes giant interneurons. Also affects neuromuscular transmission in rat tissue.<ref>PMID:12097919</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1g92" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bailly, I]]
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[[Category: Large Structures]]
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[[Category: Chroboczek, J]]
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[[Category: Paraponera clavata]]
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[[Category: Dublet, B]]
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[[Category: Bailly I]]
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[[Category: Fender, P]]
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[[Category: Chroboczek J]]
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[[Category: Ferber, M L]]
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[[Category: Dublet B]]
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[[Category: Gout, E]]
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[[Category: Fender P]]
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[[Category: Michalik, J]]
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[[Category: Ferber ML]]
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[[Category: Poznanski, J]]
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[[Category: Gout E]]
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[[Category: Szolajska, E]]
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[[Category: Michalik J]]
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[[Category: Neurotoxin]]
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[[Category: Poznanski J]]
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[[Category: Sodium channel inhibitor]]
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[[Category: Szolajska E]]
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[[Category: Toxin]]
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Current revision

SOLUTION STRUCTURE OF PONERATOXIN

PDB ID 1g92

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