|
|
(8 intermediate revisions not shown.) |
Line 1: |
Line 1: |
| | | |
- | <div style="background-color:yellow;" border="1" cellpadding="5">''Warning: this is a large structure, and loading might take a long time or not happen at all.''</div>
| + | ==Atomic-level structure of the entire HIV-1 capsid== |
- | == Atomic-level structure of the entire HIV-1 capsid == | + | <SX load='3j3q' size='340' side='right' viewer='molstar' caption='[[3j3q]]' scene=''> |
- | <StructureSection load='3j3q-pdb-bundle1.pdb.gz' size='340' side='right' caption='[[3j3q]]' scene=''> | + | |
| == Structural highlights == | | == Structural highlights == |
- | [[3j3q]] is a 1355 chain structure, available for rendering on Proteopedia in 25 parts. | + | <table><tr><td colspan='2'>[[3j3q]] is a 1356 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu4 1vu4], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu5 1vu5], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu6 1vu6], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu7 1vu7], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu8 1vu8], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vu9 1vu9], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vua 1vua], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuc 1vuc], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vud 1vud], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vue 1vue], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuf 1vuf], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vug 1vug], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuh 1vuh], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vui 1vui], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuj 1vuj], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuk 1vuk], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vul 1vul], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vum 1vum], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vun 1vun], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuo 1vuo], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vup 1vup], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vuq 1vuq], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vur 1vur], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vus 1vus] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1vut 1vut]. The July 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''HIV Capsid'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_7 10.2210/rcsb_pdb/mom_2013_7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3J3Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3J3Q FirstGlance]. <br> |
- | You may render each one of these parts individually by selecting here: <jmol><jmolMenu>
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy</td></tr> |
- | <item>
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3j3q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3j3q OCA], [https://pdbe.org/3j3q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3j3q RCSB], [https://www.ebi.ac.uk/pdbsum/3j3q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3j3q ProSAT]</span></td></tr> |
- | <script>
| + | </table> |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | == Function == |
- | echo Loading part 1 ...; refresh;
| + | [https://www.uniprot.org/uniprot/Q79791_9HIV1 Q79791_9HIV1] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS000071_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS000071_004_011858] |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle1.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 1</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 2 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle2.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 2</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 3 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle3.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 3</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 4 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle4.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 4</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 5 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle5.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 5</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 6 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle6.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 6</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 7 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle7.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 7</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 8 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle8.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 8</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 9 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle9.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 9</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 10 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle10.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 10</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 11 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle11.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 11</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 12 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle12.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 12</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 13 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle13.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 13</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 14 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle14.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 14</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 15 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle15.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 15</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 16 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle16.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 16</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 17 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle17.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 17</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 18 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle18.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 18</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 19 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle19.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 19</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 20 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle20.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script> | + | |
- | <text>render part 20</text> | + | |
- | </item> | + | |
- | <item> | + | |
- | <script> | + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 21 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle21.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script> | + | |
- | <text>render part 21</text> | + | |
- | </item> | + | |
- | <item> | + | |
- | <script> | + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 22 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle22.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 22</text> | + | |
- | </item> | + | |
- | <item> | + | |
- | <script> | + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 23 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle23.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 23</text>
| + | |
- | </item>
| + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 24 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle24.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script> | + | |
- | <text>render part 24</text> | + | |
- | </item> | + | |
- | <item>
| + | |
- | <script>
| + | |
- | set echo off; set echo loading 50% 50%; set echo loading center; color echo [xffa500]; background echo translucent 0.7 gray;
| + | |
- | echo Loading part 25 ...; refresh;
| + | |
- | load models {0 0 1} /cgi-bin/getlateststructure?3j3q-pdb-bundle25.pdb.gz filter "*.CA,*.P|HETATM,![HOH]";
| + | |
- | script /wiki/extensions/Proteopedia/spt/initialview01.spt;
| + | |
- | </script>
| + | |
- | <text>render part 25</text>
| + | |
- | </item>
| + | |
- | </jmolMenu></jmol>
| + | |
- | | + | |
| <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
Line 241: |
Line 17: |
| From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> |
| </div> | | </div> |
| + | <div class="pdbe-citations 3j3q" style="background-color:#fffaf0;"></div> |
| | | |
| + | ==See Also== |
| + | *[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] |
| == References == | | == References == |
| <references/> | | <references/> |
- | </StructureSection> | + | __TOC__ |
- | [[Category: Zhao, G]] | + | </SX> |
- | [[Category: Zhang, P]] | + | [[Category: HIV Capsid]] |
- | [[Category: Schulten, K.J]] | + | [[Category: Human immunodeficiency virus 1]] |
- | [[Category: Perilla, J.R]] | + | [[Category: Large Structures]] |
| + | [[Category: RCSB PDB Molecule of the Month]] |
| + | [[Category: Perilla JR]] |
| + | [[Category: Schulten KJ]] |
| + | [[Category: Zhang P]] |
| + | [[Category: Zhao G]] |