This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1vr3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:42, 25 January 2023) (edit) (undo)
 
(15 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1vr3.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution==
-
|PDB= 1vr3 |SIZE=350|CAPTION= <scene name='initialview01'>1vr3</scene>, resolution 2.06&Aring;
+
<StructureSection load='1vr3' size='340' side='right'caption='[[1vr3]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNL:'>UNL</scene> and <scene name='pdbligand=IPA:ISOPROPYL ALCOHOL'>IPA</scene>
+
<table><tr><td colspan='2'>[[1vr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VR3 FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=UNL:UNKNOWN+LIGAND'>UNL</scene></td></tr>
-
|GENE=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vr3 OCA], [https://pdbe.org/1vr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vr3 RCSB], [https://www.ebi.ac.uk/pdbsum/1vr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vr3 ProSAT], [https://www.topsan.org/Proteins/JCSG/1vr3 TOPSAN]</span></td></tr>
-
}}
+
</table>
-
 
+
== Function ==
-
'''Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution'''
+
[https://www.uniprot.org/uniprot/MTND_MOUSE MTND_MOUSE] Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14 (By similarity).[HAMAP-Rule:MF_03154]
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
1VR3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VR3 OCA].
+
<jmolCheckbox>
-
 
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vr/1vr3_consurf.spt"</scriptWhenChecked>
-
==Reference==
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
Crystal structure of acireductone dioxygenase (ARD) from Mus musculus at 2.06 angstrom resolution., Xu Q, Schwarzenbacher R, Krishna SS, McMullan D, Agarwalla S, Quijano K, Abdubek P, Ambing E, Axelrod H, Biorac T, Canaves JM, Chiu HJ, Elsliger MA, Grittini C, Grzechnik SK, DiDonato M, Hale J, Hampton E, Han GW, Haugen J, Hornsby M, Jaroszewski L, Klock HE, Knuth MW, Koesema E, Kreusch A, Kuhn P, Miller MD, Moy K, Nigoghossian E, Paulsen J, Reyes R, Rife C, Spraggon G, Stevens RC, van den Bedem H, Velasquez J, White A, Wolf G, Hodgson KO, Wooley J, Deacon AM, Godzik A, Lesley SA, Wilson IA, Proteins. 2006 Aug 15;64(3):808-13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16783794 16783794]
+
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vr3 ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Single protein]]
 
-
[[Category: JCSG, Joint Center for Structural Genomics.]]
 
-
[[Category: IPA]]
 
-
[[Category: NI]]
 
-
[[Category: UNL]]
 
-
[[Category: 13543033]]
 
-
[[Category: acireductone dioxygenase]]
 
-
[[Category: jcsg]]
 
-
[[Category: joint center for structural genomic]]
 
-
[[Category: protein structure initiative]]
 
-
[[Category: psi]]
 
-
[[Category: structural genomic]]
 
- 
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:48:42 2008''
 

Current revision

Crystal structure of Acireductone dioxygenase (13543033) from Mus musculus at 2.06 A resolution

PDB ID 1vr3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vr3"
Personal tools