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4f86

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==Structure analysis of Geranyl diphosphate methyltransferase in complex with GPP and sinefungin==
==Structure analysis of Geranyl diphosphate methyltransferase in complex with GPP and sinefungin==
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<StructureSection load='4f86' size='340' side='right' caption='[[4f86]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='4f86' size='340' side='right'caption='[[4f86]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f86]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lasaliensis Streptomyces lasaliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F86 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F86 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f86]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lasalocidi Streptomyces lasalocidi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F86 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F86 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4f84|4f84]], [[4f85|4f85]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gdpmt ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=324833 Streptomyces lasaliensis])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f86 OCA], [https://pdbe.org/4f86 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f86 RCSB], [https://www.ebi.ac.uk/pdbsum/4f86 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f86 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f86 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f86 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4f86 RCSB], [http://www.ebi.ac.uk/pdbsum/4f86 PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GPPMT_STRLS GPPMT_STRLS]] Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).
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[https://www.uniprot.org/uniprot/GPPMT_STRLS GPPMT_STRLS] Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4f86" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptomyces lasaliensis]]
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[[Category: Large Structures]]
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[[Category: Ariyawutthiphan, O]]
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[[Category: Streptomyces lasalocidi]]
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[[Category: Gao, Y G]]
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[[Category: Ariyawutthiphan O]]
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[[Category: Minami, A]]
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[[Category: Gao YG]]
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[[Category: Oikawa, H]]
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[[Category: Minami A]]
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[[Category: Ose, T]]
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[[Category: Oikawa H]]
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[[Category: Tanaka, I]]
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[[Category: Ose T]]
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[[Category: Yao, M]]
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[[Category: Tanaka I]]
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[[Category: Alpha/beta]]
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[[Category: Yao M]]
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[[Category: Methyltransferase]]
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[[Category: Rossmann fold]]
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[[Category: Transferase]]
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Current revision

Structure analysis of Geranyl diphosphate methyltransferase in complex with GPP and sinefungin

PDB ID 4f86

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