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1fep

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==FERRIC ENTEROBACTIN RECEPTOR==
==FERRIC ENTEROBACTIN RECEPTOR==
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<StructureSection load='1fep' size='340' side='right' caption='[[1fep]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='1fep' size='340' side='right'caption='[[1fep]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1fep]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FEP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FEP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1fep]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FEP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FEP FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fep OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fep RCSB], [http://www.ebi.ac.uk/pdbsum/1fep PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fep FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fep OCA], [https://pdbe.org/1fep PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fep RCSB], [https://www.ebi.ac.uk/pdbsum/1fep PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fep ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FEPA_ECOLI FEPA_ECOLI]] This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D.
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[https://www.uniprot.org/uniprot/FEPA_ECOLI FEPA_ECOLI] This protein is involved in the initial step of iron uptake by binding ferrienterobactin (Fe-ENT), an iron chelatin siderophore that allows E.coli to extract iron from the environment. FepA also acts as a receptor for colicins B and D.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/1fep_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/1fep_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fep ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1fep" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli k-12]]
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[[Category: Escherichia coli K-12]]
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[[Category: Buchanan, S K]]
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[[Category: Large Structures]]
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[[Category: Chakraborty, R]]
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[[Category: Buchanan SK]]
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[[Category: Deisenhofer, J]]
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[[Category: Chakraborty R]]
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[[Category: Esser, L]]
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[[Category: Deisenhofer J]]
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[[Category: Helm, D Van Der]]
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[[Category: Esser L]]
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[[Category: Palnitkar, M]]
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[[Category: Palnitkar M]]
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[[Category: Smith, B S]]
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[[Category: Smith BS]]
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[[Category: Ventatramani, L]]
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[[Category: Van Der Helm D]]
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[[Category: Xia, D]]
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[[Category: Ventatramani L]]
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[[Category: Iron transport]]
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[[Category: Xia D]]
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[[Category: Membrane protein]]
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[[Category: Outer membrane]]
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[[Category: Receptor]]
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[[Category: Tonb]]
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[[Category: Transport]]
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Current revision

FERRIC ENTEROBACTIN RECEPTOR

PDB ID 1fep

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