4lc2
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of the bromodomain of human BRPF1B== | ==Crystal structure of the bromodomain of human BRPF1B== | ||
| - | <StructureSection load='4lc2' size='340' side='right' caption='[[4lc2]], [[Resolution|resolution]] 1.65Å' scene=''> | + | <StructureSection load='4lc2' size='340' side='right'caption='[[4lc2]], [[Resolution|resolution]] 1.65Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4lc2]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4lc2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LC2 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lc2 OCA], [https://pdbe.org/4lc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lc2 RCSB], [https://www.ebi.ac.uk/pdbsum/4lc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lc2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BRPF1_HUMAN BRPF1_HUMAN] Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2.<ref>PMID:16387653</ref> <ref>PMID:18794358</ref> |
| + | |||
| + | ==See Also== | ||
| + | *[[Peregrin|Peregrin]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 14: | Line 18: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Filippakopoulos | + | [[Category: Filippakopoulos P]] |
| - | [[Category: Knapp | + | [[Category: Knapp S]] |
| - | [[Category: Nunez-Alonso | + | [[Category: Nunez-Alonso G]] |
| - | [[Category: Picaud | + | [[Category: Picaud S]] |
| - | + | [[Category: Savitsky P]] | |
| - | [[Category: Savitsky | + | [[Category: Tallant C]] |
| - | [[Category: Tallant | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the bromodomain of human BRPF1B
| |||||||||||
