This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3vpp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:31, 8 November 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Crystal Structure of the Human CLEC9A C-type Lectin-Like Domain==
==Crystal Structure of the Human CLEC9A C-type Lectin-Like Domain==
-
<StructureSection load='3vpp' size='340' side='right' caption='[[3vpp]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
+
<StructureSection load='3vpp' size='340' side='right'caption='[[3vpp]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3vpp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VPP FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3vpp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VPP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VPP FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.642&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CLEC9A, UNQ9341/PRO34046 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vpp RCSB], [http://www.ebi.ac.uk/pdbsum/3vpp PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vpp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vpp OCA], [https://pdbe.org/3vpp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vpp RCSB], [https://www.ebi.ac.uk/pdbsum/3vpp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vpp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/CLC9A_HUMAN CLC9A_HUMAN]] Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.<ref>PMID:18497879</ref> <ref>PMID:22483802</ref>
+
[https://www.uniprot.org/uniprot/CLC9A_HUMAN CLC9A_HUMAN] Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner.<ref>PMID:18497879</ref> <ref>PMID:22483802</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 17: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 3vpp" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
-
[[Category: Colman, P M]]
+
[[Category: Large Structures]]
-
[[Category: Czabotar, P E]]
+
[[Category: Colman PM]]
-
[[Category: Lahoud, M H]]
+
[[Category: Czabotar PE]]
-
[[Category: Policheni, A N]]
+
[[Category: Lahoud MH]]
-
[[Category: Shortman, K]]
+
[[Category: Policheni AN]]
-
[[Category: Zhang, J G]]
+
[[Category: Shortman K]]
-
[[Category: C-type lectin-like domain]]
+
[[Category: Zhang JG]]
-
[[Category: Dendritic cell]]
+
-
[[Category: Immune system]]
+
-
[[Category: Membrane]]
+

Current revision

Crystal Structure of the Human CLEC9A C-type Lectin-Like Domain

PDB ID 3vpp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3vpp"
Personal tools