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4lap

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==Endothiapepsin in complex with thiophen-based inhibitor SAP114==
==Endothiapepsin in complex with thiophen-based inhibitor SAP114==
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<StructureSection load='4lap' size='340' side='right' caption='[[4lap]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
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<StructureSection load='4lap' size='340' side='right'caption='[[4lap]], [[Resolution|resolution]] 1.12&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4lap]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LAP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LAP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4lap]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LAP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LAP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1VT:N-BENZYL-2-[(N-BENZYL-BETA-ALANYL)AMINO]-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>1VT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1VT:N-BENZYL-2-[(N-BENZYL-BETA-ALANYL)AMINO]-4-PHENYLTHIOPHENE-3-CARBOXAMIDE'>1VT</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3t7x|3t7x]], [[4l6b|4l6b]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lap OCA], [https://pdbe.org/4lap PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lap RCSB], [https://www.ebi.ac.uk/pdbsum/4lap PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lap ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lap FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lap OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lap RCSB], [http://www.ebi.ac.uk/pdbsum/4lap PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
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==See Also==
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*[[Pepsin|Pepsin]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cryphonectria parasitica]]
[[Category: Cryphonectria parasitica]]
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[[Category: Endothiapepsin]]
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[[Category: Large Structures]]
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[[Category: Heine, A]]
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[[Category: Heine A]]
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[[Category: Klebe, G]]
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[[Category: Klebe G]]
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[[Category: Park, A]]
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[[Category: Park A]]
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[[Category: Aspartate protease]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhibitor complex]]
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Current revision

Endothiapepsin in complex with thiophen-based inhibitor SAP114

PDB ID 4lap

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