4nni
From Proteopedia
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==Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide== | ==Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide== | ||
| - | <StructureSection load='4nni' size='340' side='right' caption='[[4nni]], [[Resolution|resolution]] 2.64Å' scene=''> | + | <StructureSection load='4nni' size='340' side='right'caption='[[4nni]], [[Resolution|resolution]] 2.64Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nni]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNI OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4nni]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNI FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.64Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=VGL:PYRAZINE-2-CARBOXYLIC+ACID'>VGL</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nni OCA], [https://pdbe.org/4nni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nni RCSB], [https://www.ebi.ac.uk/pdbsum/4nni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nni ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/RS1_MYCTU RS1_MYCTU] Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity). |
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| + | ==See Also== | ||
| + | *[[Ribosomal protein S1|Ribosomal protein S1]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: | + | [[Category: Cai Q]] |
| - | [[Category: | + | [[Category: Lin D]] |
| - | [[Category: | + | [[Category: Liu Y]] |
| - | [[Category: | + | [[Category: Yang J]] |
Current revision
Structural basis for targeting the ribosomal protein S1 of Mycobacterium tuberculosis by pyrazinamide
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