1wl8

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[[Image:1wl8.gif|left|200px]]
 
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{{Structure
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==Crystal structure of PH1346 protein from Pyrococcus horikoshii==
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|PDB= 1wl8 |SIZE=350|CAPTION= <scene name='initialview01'>1wl8</scene>, resolution 1.45&Aring;
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<StructureSection load='1wl8' size='340' side='right'caption='[[1wl8]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
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<table><tr><td colspan='2'>[[1wl8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WL8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WL8 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/GMP_synthase_(glutamine-hydrolyzing) GMP synthase (glutamine-hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.5.2 6.3.5.2]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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|GENE=
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=SNN:L-3-AMINOSUCCINIMIDE'>SNN</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wl8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wl8 OCA], [https://pdbe.org/1wl8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wl8 RCSB], [https://www.ebi.ac.uk/pdbsum/1wl8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wl8 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wl8 TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUAAA_PYRHO GUAAA_PYRHO] Catalyzes the synthesis of GMP from XMP (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wl/1wl8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wl8 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of PH1346 protein from Pyrococcus horikoshii'''
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==See Also==
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*[[GMP synthase|GMP synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1WL8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WL8 OCA].
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[[Category: Large Structures]]
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[[Category: GMP synthase (glutamine-hydrolyzing)]]
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[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Single protein]]
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[[Category: Kunishima N]]
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[[Category: Kunishima, N.]]
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[[Category: Lokanath NK]]
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[[Category: Lokanath, N K.]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: ACY]]
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[[Category: CL]]
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[[Category: gatase]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:58:25 2008''
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Current revision

Crystal structure of PH1346 protein from Pyrococcus horikoshii

PDB ID 1wl8

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