1wuf
From Proteopedia
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- | [[Image:1wuf.gif|left|200px]] | ||
- | + | ==Crystal structure of protein GI:16801725, member of Enolase superfamily from Listeria innocua Clip11262== | |
- | + | <StructureSection load='1wuf' size='340' side='right'caption='[[1wuf]], [[Resolution|resolution]] 2.90Å' scene=''> | |
- | + | == Structural highlights == | |
- | | | + | <table><tr><td colspan='2'>[[1wuf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_innocua_Clip11262 Listeria innocua Clip11262]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUF FirstGlance]. <br> |
- | | | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
- | | | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wuf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wuf OCA], [https://pdbe.org/1wuf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wuf RCSB], [https://www.ebi.ac.uk/pdbsum/1wuf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wuf ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1wuf TOPSAN]</span></td></tr> | |
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/MENC_LISIN MENC_LISIN] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24872444). Also acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine (PubMed:24872444). L.innocua has the menaquinone synthesis pathway, indicating that the species requires OSBS activity. However, the NSAR/OSBS is not encoded in the menaquinone operon, raising the possibility that both NSAR and OSBS are biological functions (PubMed:24872444).<ref>PMID:24872444</ref> | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wuf_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wuf ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
- | + | ==See Also== | |
- | + | *[[Enolase 3D structures|Enolase 3D structures]] | |
- | + | == References == | |
- | == | + | <references/> |
- | + | __TOC__ | |
- | [[Category: | + | </StructureSection> |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Almo | + | [[Category: Listeria innocua Clip11262]] |
- | [[Category: Burley | + | [[Category: Almo SC]] |
- | [[Category: Fedorov | + | [[Category: Burley SK]] |
- | [[Category: Fedorov | + | [[Category: Fedorov AA]] |
- | [[Category: Gerlt | + | [[Category: Fedorov EV]] |
- | + | [[Category: Gerlt JA]] | |
- | [[Category: Yew | + | [[Category: Yew WS]] |
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Current revision
Crystal structure of protein GI:16801725, member of Enolase superfamily from Listeria innocua Clip11262
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