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1h2s

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==MOLECULAR BASIS OF TRANSMENBRANE SIGNALLING BY SENSORY RHODOPSIN II-TRANSDUCER COMPLEX==
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<StructureSection load='1h2s' size='340' side='right' caption='[[1h2s]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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==Molecular basis of transmenbrane signalling by sensory rhodopsin II-transducer complex==
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<StructureSection load='1h2s' size='340' side='right'caption='[[1h2s]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1h2s]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Natronomonas_pharaonis Natronomonas pharaonis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H2S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H2S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1h2s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Natronomonas_pharaonis Natronomonas pharaonis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H2S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gu8|1gu8]], [[1gue|1gue]], [[1h68|1h68]], [[1jgj|1jgj]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BOG:B-OCTYLGLUCOSIDE'>BOG</scene>, <scene name='pdbligand=RET:RETINAL'>RET</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h2s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h2s RCSB], [http://www.ebi.ac.uk/pdbsum/1h2s PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h2s OCA], [https://pdbe.org/1h2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h2s RCSB], [https://www.ebi.ac.uk/pdbsum/1h2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h2s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BACS2_NATPH BACS2_NATPH]] Involved in the control of phototaxis. Seems to activate a methyl-accepting protein (HTR-II). Photoreceptor for blue light. [[http://www.uniprot.org/uniprot/HTR2_NATPH HTR2_NATPH]] Transduces signals from the phototaxis receptor sensory rhodopsin II (SR-II) to the flagellar motor. Responds to light changes through the variation of the level of methylation. Also acts as a chemotransducer.
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[https://www.uniprot.org/uniprot/BACS2_NATPH BACS2_NATPH] Involved in the control of phototaxis. Seems to activate a methyl-accepting protein (HTR-II). Photoreceptor for blue light.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/1h2s_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h2/1h2s_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h2s ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1h2s" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Bacteriorhodopsin|Bacteriorhodopsin]]
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*[[Bacteriorhodopsin 3D structures|Bacteriorhodopsin 3D structures]]
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*[[Rhodopsin|Rhodopsin]]
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*[[Rhodopsin 3D structures|Rhodopsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Natronomonas pharaonis]]
[[Category: Natronomonas pharaonis]]
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[[Category: Bueldt, G]]
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[[Category: Bueldt G]]
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[[Category: Efremov, R]]
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[[Category: Efremov R]]
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[[Category: Engelhard, M]]
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[[Category: Engelhard M]]
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[[Category: Gordeliy, V I]]
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[[Category: Gordeliy VI]]
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[[Category: Granzin, J]]
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[[Category: Granzin J]]
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[[Category: Klare, J P]]
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[[Category: Klare JP]]
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[[Category: Labahn, J]]
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[[Category: Labahn J]]
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[[Category: Moukhametzianov, R]]
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[[Category: Moukhametzianov R]]
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[[Category: Savopol, T]]
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[[Category: Savopol T]]
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[[Category: Scheidig, A]]
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[[Category: Scheidig A]]
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[[Category: Schlesinger, R]]
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[[Category: Schlesinger R]]
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[[Category: Membrane protein]]
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[[Category: Menbrane protein complex]]
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[[Category: Signal transduction]]
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Current revision

Molecular basis of transmenbrane signalling by sensory rhodopsin II-transducer complex

PDB ID 1h2s

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